alexa Differential adhesion of pathogenic Candida species to epithelial and inert surfaces


Clinical Microbiology: Open Access

Author(s): Ian A Critchley, LJulia Douglas

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Growth in medium containing 500 mM galactose is known to promote the adhesion of Candida albicans to buccal epithelial cells or to acrylic in vitro. Of 5 other Candida species tested, only C. tropicalis (one strain) showed substantially increased adhesion to buccal cells (but not to acrylic) after growth under these conditions. A second strain of C. tropicalis as well as C. stellatoidea, C. parapsilosis, C. pseudotropicalis, C. guilliermondii and Saccharomyces cerevisiae showed little or no increased adhesion to either surface. However, after growth in medium containing 50 mM glucose, C. tropicalis and C. parapsilosis were significantly more adherent to acrylic than glucose-grown yeasts of the other species, including C. albicans. These results are discussed in relation to the colonization and infection potential of the pathogenic Candida species.

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This article was published in FEMS Microbiol Lett and referenced in Clinical Microbiology: Open Access

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