alexa Diffuse correlation spectroscopy for non-invasive, micro-vascular cerebral blood flow measurement.
Medicine

Medicine

Anatomy & Physiology: Current Research

Author(s): Durduran T, Yodh AG

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Abstract Diffuse correlation spectroscopy (DCS) uses the temporal fluctuations of near-infrared (NIR) light to measure cerebral blood flow (CBF) non-invasively. Here, we provide a brief history of DCS applications in the brain with an emphasis on the underlying physical ideas, common instrumentation and validation. Then we describe recent clinical research that employs DCS-measured CBF as a biomarker of patient well-being, and as an indicator of hemodynamic and metabolic responses to functional stimuli. Copyright © 2013 Elsevier Inc. All rights reserved.
This article was published in Neuroimage and referenced in Anatomy & Physiology: Current Research

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