alexa [Diffusion-weighted MRI in sporadic Creutzfeldt-Jakob disease].


Internal Medicine: Open Access

Author(s): Nougaret S, Brunel H, Bourbotte G, Bonaf A, Nougaret S, Brunel H, Bourbotte G, Bonaf A

Abstract Share this page

Abstract Conventional MRI with T1, T2 and FLAIR sequences has an important role for the diagnosis of Creutzfeldt-Jakob disease, but the usual examination does not exclude the disease. The objective of this study is to report on the role of diffusion-weighted imaging (DWI) in the diagnostic strategy. From 2002 to 2006, four patients with a suspected diagnosis of sporadic Creutzfeldt-Jakob disease, which was retrospectively confirmed, underwent DWI. In all patients, MRI demonstrated high-signal intensities on FLAIR sequences and on spin-echo T2-weighted MRI, with restricted diffusion of caudate and lenticular nuclei. In one patient, DWI revealed cortical high-signal intensities that were not visualized on either FLAIR or T2-weighted MRI. In two other patients, MRI showed restricted thalamic diffusion, which is a classic sign of the new variant of the disease. Thus, thalamic involvement can be found in the sporadic form of the disease. It can be revealed on DWI and by apparent diffusion coefficient (ADC) mapping or detected only by ADC measurement. This article was published in J Neuroradiol and referenced in Internal Medicine: Open Access

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

  • 22nd World Cardiology Conference
    December 11-12, 2017 Rome, Italy

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

1-702-714-7001Extn: 9037

Business & Management Journals


1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version