alexa Direct evidence for expression of dopamine receptors in astrocytes from basal ganglia.


Journal of Addiction Research & Therapy

Author(s): Miyazaki I, Asanuma M, DiazCorrales FJ, Miyoshi K, Ogawa N

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Abstract Expression of dopamine receptors (DA-Rs) in astrocytes was examined in vitro and in vivo using primary cultured astrocytes and brain slices from rat basal ganglia. Astrocytes from basal ganglia expressed DA D1-, D3-, D4- and D5-receptors and D4-mediated signal transduction in response to DA, suggesting possible involvement of astrocytes in the pharmacological action of atypical antipsychotic drugs and in DA response in some neurological diseases. This article was published in Brain Res and referenced in Journal of Addiction Research & Therapy

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