alexa Direct high-resolution peptide and protein analysis by desorption electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry.
Chemical Engineering

Chemical Engineering

Journal of Analytical & Bioanalytical Techniques

Author(s): Bereman MS, Nyadong L, Fernandez FM, Muddiman DC

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Abstract We report the first coupling of a desorption electrospray ionization (DESI) ion source to Fourier transform ion cyclotron resonance mass spectrometry (ESI-FT-ICR-MS) for high-resolution protein analysis. The DESI FT-ICR-MS source design is described in detail along with preliminary data obtained on peptides and proteins ranging from 1 to 5.7 kDa. Copyright 2006 John Wiley & Sons, Ltd. This article was published in Rapid Commun Mass Spectrom and referenced in Journal of Analytical & Bioanalytical Techniques

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