alexa Distressful symptoms and well-being after radical cystectomy and orthotopic bladder substitution compared with a matched control population.
Oncology

Oncology

Journal of Cancer Science & Therapy

Author(s): Henningsohn L, Steven K, Kallestrup EB, Steineck G

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Abstract PURPOSE: We compared subjective quality of life, well-being, urinary tract symptoms and distress in patients after radical cystectomy and orthotopic urinary reconstruction with those in a matched control population. MATERIALS AND METHODS: Included in this study were 101 consecutive recurrence-free patients who underwent radical cystectomy and orthotopic bladder substitution with an ileal urethral Kock neobladder at Herlev Hospital with a minimum followup of 1 year. A frequency matched control group comprising 147 individuals was selected from the same geographical region. Information was collected by an anonymous postal questionnaire and analyzed externally in Sweden. RESULTS: The prevalence of low or moderate psychological well-being (32\% versus 36\%) and subjective quality of life (30\% versus 38\%), and high or moderate anxiety (23\% versus 18\%) and depression (26\% versus 37\%) was similar in patients with an orthotopic neobladder and population controls. Patients with a neobladder felt as attractive as the control population. Of the operated men 94\% had erectile dysfunction compared with 48\% of controls. Daytime and nighttime urinary frequency was similar in patients and controls (3\% and 3\%, and 15\% and 13\%, respectively), while the prevalence of urinary leakage at least once monthly was higher in patients (18\% versus 5\%). Intermittent self-catheterization was performed by 26\% of patients with a neobladder. Urinary tract infection (14\% versus 6\%) was more common and the prevalence of distressful bowel symptoms (14\% versus 9\%) was slightly more common in patients than in controls. CONCLUSIONS: Well-being and subjective quality of life in patients after radical cystectomy and orthotopic bladder substitution were similar to those in a matched control population.
This article was published in J Urol and referenced in Journal of Cancer Science & Therapy

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