Author(s): Prakash D, Saxena RS
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Abstract Urinary tract infection is one of the common infections in the Indian community. Distribution and susceptibility of UTI-causing pathogens change according to time and place. This study was conducted to determine the distribution and antimicrobial susceptibility of uropathogens in the Indian community as well as to determine the effect of gender and age on the etiology of bacterial uropathogens. Clean catch midstream urine samples were collected from 288 patients of the age ranging from 15 to ≥48 years. Antimicrobial susceptibility was performed on all isolated bacteria by Kirby Bauer's disc diffusion method. The multiple antibiotic resistance (MAR) index of each antibiotic was calculated. The UTI prevalence was 53.82\% in patients; however, the prevalence was significantly higher in females than in males (females: 73.57\%; males: 35.14\%; P = 0.000). Females within the age group of 26-36 years and elderly males of ≥48 years showed higher prevalence of UTI. Gram negative bacteria (90.32\%) were found in high prevalence than Gram positive (9.68\%). Escherichia coli (42.58\%) was the most prevalent gram negative isolate. Nitrofurantoin (78.71\%) was found the most resistant drug among all uropathogens. Tested carbapenems were found the most susceptible drug against isolated uropathogens which showed 92.26\% and 84.52\% susceptibility, respectively.
This article was published in ISRN Microbiol
and referenced in Journal of Addiction Research & Therapy