alexa Distribution of vascular resistance and compliance in a dog lung lobe.
Materials Science

Materials Science

Journal of Nanomedicine & Nanotechnology

Author(s): Linehan JH, Dawson CA, Rickaby DA

Abstract Share this page

Abstract We have modeled the left lower dog lung lobe as three serial compartments, each containing resistance (R) and compliance (C). The intracompartmental arrangement of R and C was chosen to permit their evaluation from pressure data obtained following occlusion of the venous outflow. We found that two mathematically distinct models permitted evaluation of the distribution of R and C. The models were complementary in that when used together the R and C of the three compartments could be determined. The central compartment had 46\% of the lobar vascular resistance and 75\% of the lobar vascular compliance under control conditions. We found that serotonin and histamine, which increased the resistance proximal and distal to the central compartment, respectively, did not increase the central resistance. Therefore, we conclude that the central compartment includes the capillary bed. The equilibrium pressure (Pd), obtained when arterial inflow and venous outflow were simultaneously occluded, was in close agreement with the average preocclusion pressure of the central compartment, indicating that Pd is close to the pulmonary microvascular pressure.
This article was published in J Appl Physiol Respir Environ Exerc Physiol and referenced in Journal of Nanomedicine & Nanotechnology

Relevant Expert PPTs

Recommended Conferences

  • Nano Congress for Next Generation
    August 31-September 01, 2017 Brussels,Belgium
  • Graphene & 2D Materials
    September 14-15, 2017 Edinburgh, Scotland
  • Graphene & 2D Materials
    November 6-7, 2017 Frankfurt, Germany
  • World Congress on Nanoscience and Nano Technology
    October 16-17, 2017 Dubai, UAE
  • World Medical Nanotechnology Congress
    October 18-19, 2017 Osaka, Japan
  • Nanoscienceand Molecular Nanotechnology
    Nov 06-08, 2017 Frankfurt, Germany
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords