alexa Diurnal cortisol variation is associated with nocturnal blood pressure dipping.
Diabetes & Endocrinology

Diabetes & Endocrinology

Journal of Steroids & Hormonal Science

Author(s): HoltLunstad J, Steffen PR

Abstract Share this page

Abstract OBJECTIVE: To investigate if diurnal cortisol variation is associated with nocturnal blood pressure (BP) dipping. METHODS: In this study, 302 healthy adults (51\% female; average age 31 years) underwent 24-hour ambulatory BP assessment with BP measured randomly approximately every 20 minutes during waking hours and every hour during sleep. Salivary cortisol was obtained at five time points. Cortisol and BP have natural diurnal variations and disruptions in these diurnal variations are related to pathological conditions, such as greater risk for cardiovascular disease. A lack of a drop in cortisol from day to night and a lack of a drop in BP from waking to sleeping have both been associated with negative outcomes. It is not known, however, if diurnal variations in cortisol and BP are related, or if changes in cortisol from day to night influence BP dipping. RESULTS: Diurnal cortisol variation was a significant predictor of BP dipping. Controlling for gender, body mass index, age, phase of menstrual cycle, sleep quality, morning cortisol, and daytime measures of the relevant cardiovascular assessments did not significantly affect the results. Cortisol variation was found to have a stronger relationship with BP dipping than any of the covariates measured. CONCLUSION: Decreased diurnal variation in cortisol is associated with decreased diurnal variation in BP. Future studies could benefit from examining how these two variables interact in predicting disease outcomes. This article was published in Psychosom Med and referenced in Journal of Steroids & Hormonal Science

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords