Author(s): Reed JC, Reed JC
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Abstract Bcl-2 is an oncogenic protein that acts by inhibiting programmed cell death. The mechanisms used by this and related anti-apoptotic proteins to protect cells from cytotoxic stimuli are now emerging, with the discovery that Bcl-2 can function both as an ion channel and as an adaptor or docking protein.
This article was published in Nature
and referenced in Journal of Blood Disorders & Transfusion