alexa Drug discovery from natural sources.
Chemistry

Chemistry

Natural Products Chemistry & Research

Author(s): Chin YW, Balunas MJ, Chai HB, Kinghorn AD

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Abstract Organic compounds from terrestrial and marine organisms have extensive past and present use in the treatment of many diseases and serve as compounds of interest both in their natural form and as templates for synthetic modification. Over 20 new drugs launched on the market between 2000 and 2005, originating from terrestrial plants, terrestrial microorganisms, marine organisms, and terrestrial vertebrates and invertebrates, are described. These approved substances, representative of very wide chemical diversity, together with several other natural products or their analogs undergoing clinical trials, continue to demonstrate the importance of compounds from natural sources in modern drug discovery efforts.
This article was published in AAPS J and referenced in Natural Products Chemistry & Research

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