alexa Dynamic multichannel near-infrared optical imaging of human brain activity.


Biochemistry & Analytical Biochemistry

Author(s): Hoshi Y, Tamura M

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Abstract The present paper demonstrates functional brain mapping with an optical imaging technique by using tissue-transparent near-infrared light. With a maximal five-channel optical monitoring system, we succeeded in detecting region-specific changes in both the hemoglobin oxygenation state and blood volume during various mental tasks, in addition to visual and auditory stimulation. The time course of increases in blood supply varied with each brain region and depended on the type of internal operations occurring during the mental tasks. Changes in the hemoglobin oxygenation state were also different from region to region. This showed that there were regional variations of the oxygen delivery-oxygen utilization relationship during activation of brain activity. The usefulness of multichannel near-infrared functional imaging was well documented.
This article was published in J Appl Physiol (1985) and referenced in Biochemistry & Analytical Biochemistry

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