alexa Ear lobe bilateral necrosis by levamisole-induced occlusive vasculitis in a pediatric patient.
Orthopaedics

Orthopaedics

Journal of Arthritis

Author(s): Menni S, Pistritto G, Gianotti R, Ghio L, Edefonti A, Menni S, Pistritto G, Gianotti R, Ghio L, Edefonti A, Menni S, Pistritto G, Gianotti R, Ghio L, Edefonti A

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Abstract We describe a bullous-hemorrhagic reaction of the ear lobes in a child with nephrosis after levamisole intake. This drug is used in children as an alternative treatment of corticosteroid-responsive nephrotic syndrome. Histologic evaluation of a lesion revealed necrotizing vasculitis involving mainly the large vessels of the deep plexus. The lesions disappeared 25 days after discontinuation of treatment.
This article was published in Pediatr Dermatol and referenced in Journal of Arthritis

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