alexa Efavirenz to nevirapine switch in HIV-1-infected patients with dyslipidemia: a randomized, controlled study.
Microbiology

Microbiology

Journal of Antivirals & Antiretrovirals

Author(s): Parienti JJ, Massari V, Rey D, Poubeau P, Verdon R SIROCCO study

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Abstract Many antiretroviral therapies, including efavirenz, are associated with increased serum concentrations of low-density lipoprotein cholesterol. In a small 52-week randomized study, we found that switching from efavirenz to nevirapine was associated with significantly decreased low-density lipoprotein cholesterol levels, compared with continuation of efavirenz therapy (P<.04). A switch to nevirapine was associated with no severe adverse events. This article was published in Clin Infect Dis and referenced in Journal of Antivirals & Antiretrovirals

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