alexa Effect of early long-pulse pulsed dye laser treatment in infantile hemangiomas.
Reproductive Medicine

Reproductive Medicine

Journal of Pregnancy and Child Health

Author(s): Kwon SH, Choi JW, Byun SY, Kim BR, Park KC,

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Abstract BACKGROUND: Despite several recent reports on the efficacy of long-pulse pulsed dye laser (LP-PDL) in treating infantile hemangiomas, controversy remains. OBJECTIVES: To determine the beneficial effects of early therapeutic intervention with LP-PDL in superficial and mixed hemangiomas. METHODS AND MATERIALS: Clinical data from 40 children with 47 hemangiomas in preproliferative or proliferative phase treated with LP-PDL in a Korean tertiary hospital over 5 years were analyzed retrospectively. Treatments were repeated at 1- to 4-week intervals until growth stopped. RESULTS: Of the 47 hemangiomas, 32 were superficial, and 15 were mixed at presentation. Age was 9.6 ± 5.9 weeks at initiation of treatment and 18.0 ± 8.6 weeks at completion, and a positive linear correlation existed between the two. There were a mean of 4.6 ± 2.6 treatments per hemangioma, which was lower in superficial than in mixed hemangiomas. Improvement in color was documented in 84.4\% of superficial and 86.7\% of mixed hemangiomas, and 75.0\% of superficial and 66.7\% of mixed shrank. Hyperpigmentation occurred in two superficial hemangiomas. CONCLUSION: Early intervention in hemangiomas using LP-PDL successfully prevents further growth and accelerates a transition to plateau or involution phase with minimal adverse events, achieving good cosmetic outcomes. © 2014 by the American Society for Dermatologic Surgery, Inc. Published by Wiley Periodicals, Inc. This article was published in Dermatol Surg and referenced in Journal of Pregnancy and Child Health

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