alexa Effect of extraction solvents and plant parts used on the antihyperlipidemic and antioxidant effects of Garcinia atroviridis: a comparative study.
Pharmaceutical Sciences

Pharmaceutical Sciences

Medicinal & Aromatic Plants

Author(s): AlMansoub MA, Asmawi MZ, Murugaiyah V

Abstract Share this page

Abstract BACKGROUND: Garcinia atroviridis is a seasonal fruit plant found in many parts of South East Asia. The fruit rind is used in cooking and traditionally consumed for various reasons, including to lower blood cholesterol. A comparative study was undertaken to investigate the influence of extraction solvents and plant parts used on the lipid-lowering and antioxidant activities of Garcinia atroviridis. RESULTS: Aqueous extracts showed better antihyperlipidemic activity than the methanol extracts. Aqueous extract of ripe fruit showed the most potent antihyperlipidemic activity, comparable to that of atorvastatin. It significantly reduced the total cholesterol (P < 0.05), triglycerides (P < 0.01), low-density lipoprotein (P < 0.01), very-low-density lipoprotein (P < 0.01) and atherogenic index (P < 0.01). In contrast, antioxidant activities of methanol extracts of all parts of G. atroviridis were higher than their respective aqueous extracts, whereby the stem and leaves extracts showed better antioxidant activities than the fruits. CONCLUSION: Aqueous and methanol extracts of G. atroviridis showed higher antihyperlipidemic and antioxidant effects, respectively. Total phenolic and flavonoid contents showed significant correlations with antioxidant but not with antihyperlipidemic activities, indicating the involvement of other compounds. Contrary to the traditional belief, the present findings suggest that the fruit has higher antihyperlipidemic potential than the fruit rind. © 2013 Society of Chemical Industry. This article was published in J Sci Food Agric and referenced in Medicinal & Aromatic Plants

Relevant Expert PPTs

Relevant Speaker PPTs

  • Bonamali Pal
    Metal-TiO2 nano-photocatalysts for detoxification of toxic pesticides, dyes, polyaromatics pollutants and bacteria under UV-sunlight irradiation
    PPT Version | PDF Version

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version