Author(s): Grant EC, PryseDavies J
Abstract Share this page
Abstract Significant variations in the incidence of depression and loss of libido were found with the various types of oral contraceptives. The highest incidence occurred with strongly progestogenic compounds (especially with those containing a small amount of oestrogen) which have high monoamine oxidase activity for most of the cycle. The lowest incidence was found with the strongly oestrogenic sequential regimens which have weak monoamine oxidase activity for most of the cycle.
This article was published in Br Med J
and referenced in Journal of Cancer Clinical Trials