alexa Effect of surface topology on the osseointegration of implant materials in trabecular bone.
General Science

General Science

Journal of Biotechnology & Biomaterials

Author(s): Wong M, Eulenberger J, Schenk R, Hunziker E

Abstract Share this page

Abstract The importance of surface topology and implant material composition on osseointegration in trabecular bone was investigated using three commericially used implant materials and surface-texturing procedures which included blasting, high temperature acid etching, and hydroxyapatite (HA) coating. Surface roughness and spacing parameters were measured for each implant group with a laser interferometric profilometer. Cylindrical implants were press-fit into trabecular bone sites in the knee of mature miniature pigs. After 12 weeks in situ, osseointegration was evaluated by (1) mechanical pushout tests to measure bone-implant interface strength and (2) quantitative morphometric measurements of the percent implant surface covered by bone. We found that HA-coated implants showed superior osseointegration in terms of both pushout failure load and surface coverage by bone measurements. An excellent correlation (r2 = .90) was found between the average roughness of the implant surface and pushout failure load. New methods for altering the local topologic and/or chemical state of the implant surface (i.e., by acid etching) may provide an important new avenue of research for improving the osseointegrative properties of orthopedic materials. This article was published in J Biomed Mater Res and referenced in Journal of Biotechnology & Biomaterials

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords