alexa Effective volume of ropivacaine 0.75\% through a catheter required for interscalene brachial plexus blockade.
Anesthesiology

Anesthesiology

Journal of Anesthesia & Clinical Research

Author(s): Vandepitte C, Gautier P, Xu D, Salviz EA, Hadzic A

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Abstract BACKGROUND: Ultrasound guidance during peripheral nerve blocks has allowed for reduction in dose and volume of local anesthetic required to accomplish successful blockade using multiple injections through a needle. The authors undertook this study to determine the minimal effective volume required to accomplish successful interscalene brachial plexus block (ISB) through the catheter. METHODS: After obtaining institutional ethics committee approval and written informed consent, patients aged 18-75 yr and scheduled for arthroscopic shoulder surgery under ISB were enrolled. All patients using a step-up/step-down method and the starting dose of 15 ml of 0.75\% ropivacaine received an ultrasound-guided ISB catheter. The injection volume was increased or decreased by 1 ml in case of block failure or block success, respectively. RESULTS: The authors found that the proportion of patients with successful blockade increased sharply from approximately 57\% at 6 ml to 100\% by 7 ml, indicating that a small increase in volume of ropivacaine 0.75\% markedly affects the success rate. A total of 12 ISB with injection volume less than 7 ml resulted in successful anesthesia within 30 min, yielding an ED95 of 7 ml (95\% CI 6.8-7.2) ropivacaine 0.75\%. For the group as a whole, the median (min-max) sensory block onset time was 5 (5-20) min, the median (min-max) motor blocks for the biceps and the deltoid muscles were 7.5 (5-15) min and 10 (5-15) min, respectively. The median (min-max) block duration was 8.9 (3-15) h. CONCLUSIONS: An injection of a minimum of 7 ml of ropivacaine 0.75\% through the catheter is required for success rate and timely onset of surgical anesthesia with ISB. This article was published in Anesthesiology and referenced in Journal of Anesthesia & Clinical Research

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