Author(s): Jones RE, Heron JR, Foster DH, Snelgar RS, Mason RJ
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Abstract 4-Aminopyridine (4-AP) was administered to two groups of patients with multiple sclerosis (MS). The first group consisted of 5 patients with labile visual symptoms, 2 of whom had arcuate scotomata. 4-AP improved visual performance of most patients in this group and reduced the size of scotomata. The second group consisted of 5 patients with the spinal form of MS who were in a stable state; in this group 4-AP had little effect clinically or on tests of visual function.
This article was published in J Neurol Sci
and referenced in International Journal of Physical Medicine & Rehabilitation