alexa Effects of bacterial melanin on movement, posture, and skilled balancing deficits after unilateral destruction of substantia nigra pars compacta in rats.


Journal of Pigmentary Disorders

Author(s): Petrosyan TR, Gevorkyan OV, Hovsepyan AS, Petrosyan TR, Gevorkyan OV, Hovsepyan AS

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Abstract Sixteen adult male rats were initially trained to an instrumental conditioned reflex (ICR) and subjected to unilateral destruction of substantia nigra pars compacta. Part of the animals was injected with bacterial melanin solution on the next day of destruction. The other 8 rats served as the control group. Recovery rates for ICR and dynamics of paralyzed hindlimb movements were studied in both groups. Conditioned reflex and contralateral to lesion hindlimb movements recovered faster in rats injected with bacterial melanin after the destruction. This article was published in J Mot Behav and referenced in Journal of Pigmentary Disorders

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