alexa Effects of S-PRG eluate on oral biofilm and oral malodor.
Pharmaceutical Sciences

Pharmaceutical Sciences

Pharmaceutica Analytica Acta

Author(s): Suzuki N, Yoneda M, Haruna K, Masuo Y, Nishihara T,

Abstract Share this page

Abstract OBJECTIVES: This study evaluated the effects of a surface pre-reacted glass-ionomer (S-PRG) eluate on oral microbiota and dental biofilms in vitro, and on oral malodor and tongue bacterial loads clinically. STUDY DESIGN: The effect of S-PRG eluate on the growth and survival of salivary bacteria was examined under both aerobic and anaerobic conditions; its ability to inhibit new biofilm formation and disrupt mature biofilms was also evaluated. The concentration of volatile sulfur compounds (VSCs) was measured using a portable sulfide monitor before and after rinsing with S-PRG eluate or distilled water. The number of bacteria on the tongue surface was calculated using a portable bacterial counter before and after tongue scraping with S-PRG eluate or distilled water. RESULTS: No zone of inhibition was seen for S-PRG eluate against salivary microbiota under either aerobic or anaerobic conditions; however, treatment with ≥20\% S-PRG eluate was sufficient to suppress biofilm formation relative to untreated controls. Mature biofilms were significantly disrupted following treatment with ≥60\% S-PRG eluate relative to controls. Rinsing with S-PRG eluate significantly reduced the level of VSCs relative to baseline; this effect was not seen with distilled water alone. Waste fluids collected after oral rinsing with S-PRG eluate contained more bacteria than rinsing with distilled water alone. Finally, tongue scraping using S-PRG eluate was shown to significantly reduce the number of bacteria on the tongue surface. CONCLUSIONS: S-PRG eluate inhibits biofilm formation and disrupts mature biofilms, although its antibacterial activity is limited. Oral rinsing and tongue cleaning with S-PRG eluate may reduce oral malodor by effectively removing oral bacteria from the oral cavity. Copyright © 2014 Elsevier Ltd. All rights reserved. This article was published in Arch Oral Biol and referenced in Pharmaceutica Analytica Acta

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version