alexa Efficacy of early treatment of facial port wine stains in newborns: a review of 49 cases.
Dermatology

Dermatology

Cosmetology & Oro Facial Surgery

Author(s): Chapas AM, Eickhorst K, Geronemus RG

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Abstract BACKGROUND: Port wine stains (PWS) affect 0.3-0.5\% of both sexes of newborns, usually occurring on the face. OBJECTIVE: To document safety and effectiveness of cryogen spray cooled, pulsed-dye laser at higher fluences than previously used to lighten facial PWS in infants < or =6 months, and establish that frequent treatment early in life yields better clearance than if delayed until later in life. MATERIALS AND METHODS: Forty-nine infants who had been treated with pulsed-dye laser treatments for facial PWS at < or =6 months were identified by case review of photographs, age, sex, PWS severity score prior to laser treatment, number of treatments, and improvement following laser therapy. RESULTS: Patients averaged 9.3 (range 2-16) treatments at 4-6 week intervals at 7.75-9.5 J/cm(2). Average surface area treated was 24.0\% with 88.6\% average clearance after 1 year. Average clearance was 90.7\% for lesions covering <20\% surface area and 85.6\% for lesions > or =20\%. Location (V1, V2, V3, eye, and/or scalp), treated surface area, treatment number, and fluence predicted clearance. Average clearance for sole involvement of V1 was highest (at 93.8\%), followed by V2 (at 91.1\%), V3 (at 84.3\%), V1/V2 (at 83.7\%), V1/V2/V3 (at 81.0\%), periocular (at 88.6\%), and scalp (at 89.9\%). All patients tolerated the higher treatment fluences without atrophy or scarring. DISCUSSION/CONCLUSIONS: Frequent, high energy pulsed-dye laser treatments are safe and highly effective in improving facial PWS in infants < or =6 months of age. Patients with PWS should be referred for pulsed-dye laser treatment during early infancy. This article was published in Lasers Surg Med and referenced in Cosmetology & Oro Facial Surgery

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