alexa Efficacy of narrowband ultraviolet B twice weekly for hypopigmented mycosis fungoides in Asians.
Dermatology

Dermatology

Dermatology and Dermatologic Diseases

Author(s): Kanokrungsee S, Rajatanavin N, Rutnin S, Vachiramon V, Kanokrungsee S, Rajatanavin N, Rutnin S, Vachiramon V

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Abstract Hypopigmented mycosis fungoides (MF) is a rare variant of cutaneous T-cell lymphoma. To date, there have been no data published about the efficacy of a twice-weekly regimen of narrowband ultraviolet B (NB-UVB) for the treatment of hypopigmented MF. We retrospectively reviewed 11 patients with hypopigmented MF who were treated with NB-UVB twice weekly between 2001 and 2010. Of the 11 patients, 7 achieved a complete response with a mean of 40 treatments; the remaining 4 patients had a partial response. Upon discontinuation of treatment, three patients had clinical relapse after complete remission. Median time to relapse was 10 months. A twice-weekly regimen of NB-UVB is an effective treatment for hypopigmented MF with minimal side-effects. However, the relapse rate is high, and unfortunately, no clinical or histological features can predict the relapse of the disease. © The Author(s). CED © 2012 British Association of Dermatologists. This article was published in Clin Exp Dermatol and referenced in Dermatology and Dermatologic Diseases

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