Author(s): Gavald J, Martn MT, Lpez P, Gomis X, Ramrez JL,
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Abstract The efficacy of therapeutic aerosolized amphotericin B (AMB) was studied in a steroid-immunosuppressed murine model of invasive pulmonary aspergillosis. Nebulized liposomal AMB can be a valid approach to the treatment of this infection, with subjects showing significantly improved survival relative to that of subjects given intravenous deoxycholate AMB, as well as lower lung weights and pulmonary glucosamine levels.
This article was published in Antimicrob Agents Chemother
and referenced in Pharmaceutica Analytica Acta