alexa Ehretianone, a novel quinonoid xanthene from Ehretia buxifolia with antisnake venom activity.


Journal of Clinical Toxicology

Author(s): Selvanayagam ZE, Gnanavendhan SG, Balakrishna K, Rao RB, Sivaraman J,

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Abstract Ehretianone (1), a new quinonoid xanthene, together with known sterols, was isolated from a MeOH extract of the root bark of Ehretia buxifolia. The structure of ehretianone was elucidated as 7-hydroxy-9a alpha-(3-methylbut-2-enyl)-4a alpha,9 alpha-(2-methylprop-2-enyl)-4a, 9a-dihydro-1,4-dioxoxanthene on the basis of spectroscopic data and X-ray crystallographic analysis. The antisnake venom activity of ehretianone against Echis carinatus venom in mice is also reported. This article was published in J Nat Prod and referenced in Journal of Clinical Toxicology

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