Author(s): Kerr G, Ray G, Wu O, Stott DJ, Langhorne P
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Abstract BACKGROUND: Troponin levels are elevated in some acute stroke patients, but the clinical significance of this is unclear. METHODS: We conducted a systematic review of studies measuring troponin within 7 days of symptom onset in acute stroke patients. RESULTS: We identified 15 studies (2,901 patients). Overall 18.1\% (95\% CI 13.6-22.6) had a positive troponin level. These patients were more likely to have electrocardiogram (ECG) changes suggestive of myocardial ischemia (OR 3.0; 95\% CI 1.5-6.2), and there was an independent association with death (OR 2.9; 95\% CI 1.7-4.8). CONCLUSION: Elevated troponin level after acute stroke is common and is associated with ECG changes suggestive of myocardial ischemia and increased risk of death. Copyright (c) 2009 S. Karger AG, Basel.
This article was published in Cerebrovasc Dis
and referenced in Journal of Clinical Case Reports