Author(s): Saad Z Usmani, Susan H Tannenbaum, Poornima Hegde
Giant cell carcinoma of the lung is a rare type of primary pulmonary malignancy. It has an aggressive clinical course, and most patients present with locally advanced or metastatic disease. Its characteristic histopathologic features are well described in the literature and include emperipolesis, wherein large pleomorphic cells engulf neutrophils. Here, we describe a case of early-stage giant cell carcinoma of the lung showing this fascinating feature.