Author(s): Blijdorp K, van Waas M, van der Lely AJ, Pieters R, van den HeuvelEibrink M,
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Abstract This study focuses on the effect of chemotherapy on endocrinopathies and the metabolic syndrome in adult survivors of childhood acute myeloid leukemia (AML). Endocrine function and metabolic syndrome were evaluated in 12 AML survivors, treated with chemotherapy, and in 9 survivors of myeloid leukemias treated with stem cell transplantation (SCT), after a median follow-up time of 20 years (range 9-31). In survivors treated with chemotherapy, no endocrinopathies or metabolic syndrome were present, although AMH and Inhibin B levels tended to be lower than in controls. In SCT survivors, pituitary deficiencies and metabolic syndrome were more frequent. Copyright © 2012 Elsevier Ltd. All rights reserved.
This article was published in Leuk Res
and referenced in Journal of Antivirals & Antiretrovirals