alexa Endophthalmitis outbreaks following cataract surgery: causative organisms, etiologies, and visual acuity outcomes.
Microbiology

Microbiology

Clinical Microbiology: Open Access

Author(s): Pathengay A, Flynn HW Jr, Isom RF, Miller D

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Abstract A systematic review of 27 reports of endophthalmitis outbreaks following cataract surgery between 1985 and 2011 found the 2 most common causes associated with the outbreaks were contaminated solutions, 10 reports (37\%), and contaminated phacoemulsification machines, 6 reports (22.2\%). Other possible sources of contamination included ventilation systems, 3 (11.1\%); defective sterilization, 3 (11.1\%); miscellaneous, 3 (11.1\%); in 5 outbreaks (18.5\%), no possible source could be identified. Bacteria occurred in 23 outbreaks (85.2\%) and fungus in 4 (14.8\%). Causative organisms were gram-negative bacteria, 15 (65.2\%); gram-positive bacteria, 5 (21.7\%); and both gram-positive and gram-negative bacteria, 3 (13.1\%). Pseudomonas aeruginosa was causative in 14 of 27 (51.8\%) gram-negative bacteria. After treatment in 229 patients, a visual acuity outcome of 20/400 or better was achieved in 127 patients (55.5\%). Outbreaks of endophthalmitis following cataract surgery are often caused by gram-negative organisms and can be associated with poor visual outcomes. In this review, the most common source was irrigation solutions used perioperatively. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned. Copyright © 2012 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved. This article was published in J Cataract Refract Surg and referenced in Clinical Microbiology: Open Access

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