alexa Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications.

Journal of Clinical Diabetes & Practice

Author(s): Tabit CE, Chung WB, Hamburg NM, Vita JA

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Abstract Cardiovascular disease is a major complication of diabetes mellitus, and improved strategies for prevention and treatment are needed. Endothelial dysfunction contributes to the pathogenesis and clinical expression of atherosclerosis in diabetes mellitus. This article reviews the evidence linking endothelial dysfunction to human diabetes mellitus and experimental studies that investigated the responsible mechanisms. We then discuss the implications of these studies for current management and for new approaches for the prevention and treatment of cardiovascular disease in patients with diabetes mellitus.
This article was published in Rev Endocr Metab Disord and referenced in Journal of Clinical Diabetes & Practice

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