alexa Endothelium-Derived Nitric Oxide as an Antiatherogenic Mechanism: Implications for Therapy.
Medicine

Medicine

Translational Medicine

Author(s): Sukhovershin RA, Yepuri G, Ghebremariam YT

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Abstract Endothelium-derived nitric oxide (eNO) is a multifunctional signaling molecule critically involved in the maintenance of metabolic and cardiovascular homeostasis. In addition to its role as a potent endogenous vasodilator, eNO suppresses key processes in vascular lesion formation and opposes atherogenesis. This review discusses eNO as an antiatherogenic molecule and highlights factors that influence its bioavailability and therapeutic approaches to restore or enhance its levels.
This article was published in Methodist Debakey Cardiovasc J and referenced in Translational Medicine

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