alexa Enhanced osteoblast functions on anodized titanium with nanotube-like structures.
Genetics & Molecular Biology

Genetics & Molecular Biology

Journal of Tissue Science & Engineering

Author(s): Yao C, Slamovich EB, Webster TJ

Abstract Share this page

Abstract Previous studies have demonstrated increased osteoblast (bone-forming cells) adhesion on titanium and Ti-6Al-4V anodized to possess nanometer features compared with their unanodized counterparts. In this study, osteoblast long-term functions (specifically, synthesis of intracellular proteins, synthesis of intracellular collagen, alkaline phosphatase activity, and deposition of calcium-containing minerals) were determined on titanium anodized to possess either heterogeneous nanoparticles or ordered nanotubes. Titanium was anodized in dilute hydrofluoric acid at 20 V for 20 min to possess nanotubes, while titanium was anodized at 10 V for 20 min to possess nanoparticles. Most importantly, results showed that calcium deposition significantly increased on anodized titanium with nanotube-like structures compared with unanodized titanium and anodized titanium with nanoparticulate structures after 21 days of osteoblast culture. In this manner, the results of the present in vitro study indicated that anodization might be a promising quick and inexpensive method to modify the surface of titanium-based implants to induce better bone cell functions important for orthopedic applications. Copyright 2007 Wiley Periodicals, Inc. This article was published in J Biomed Mater Res A and referenced in Journal of Tissue Science & Engineering

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

  • 6th International Conference on Tissue Engineering and Regenerative Medicine
    August 23-24 , 2017 San Francisco, California ,USA
  • 8th International Conference on Tissue Science and Regenerative Medicine
    September 11-12, 2017 Singapore City, singapore
  • 9th Annual Conference on Stem Cell and Regenerative Medicine
    Sep 25-26, 2017 Berlin, Germany
  • 10th World Congress on Stem Cell and Biobanking
    October 23-24, 2017 Osaka, Japan

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version