alexa Environments shape the nucleotide composition of genomes.
Bioinformatics & Systems Biology

Bioinformatics & Systems Biology

Journal of Data Mining in Genomics & Proteomics

Author(s): Foerstner KU, von Mering C, Hooper SD, Bork P, Foerstner KU, von Mering C, Hooper SD, Bork P, Foerstner KU, von Mering C, Hooper SD, Bork P, Foerstner KU, von Mering C, Hooper SD, Bork P

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Abstract To test the impact of environments on genome evolution, we analysed the relative abundance of the nucleotides guanine and cytosine ('GC content') of large numbers of sequences from four distinct environmental samples (ocean surface water, farm soil, an acidophilic mine drainage biofilm and deep-sea whale carcasses). We show that the GC content of complex microbial communities seems to be globally and actively influenced by the environment. The observed nucleotide compositions cannot be easily explained by distinct phylogenetic origins of the species in the environments; the genomic GC content may change faster than was previously thought, and is also reflected in the amino-acid composition of the proteins in these habitats.
This article was published in EMBO Rep and referenced in Journal of Data Mining in Genomics & Proteomics

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