alexa Enzymes Relevant to Kojic Acid Biosynthesis in Aspergillus flavus


Fermentation Technology


Abstract Share this page

Hexokinase, glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, glucose dehydrogenase, glucose oxidase and gluconate dehydrogenase have been demonstrated in mycelial homogenates from a strain of Aspergillus flavus that produces considerable amounts of kojic acid. The enzymes were assayed after different periods of growth under different experimental conditions and their activities were compared with the rate of kojic acid production. Glucose oxidase activity was too low to account for the formation of kojic acid but the other enzymes had sufficient activities. Correlation of the pattern of enzyme activities under different experimental conditions with kojic acid concentrations provided evidence for the involvement of glucose dehydrogenase and gluconate dehydrogenase in kojic acid biosynthesis. Based on these data a possible pathway for the biosynthesis of kojic acid is presented. Gluconic acid-δ-lactone and at least one of the three compounds, 3-ketogluconic acid lactone, 3-ketoglucose and oxykojic acid, are believed to be intermediates in this pathway.

This article was published in Microbiology and referenced in Fermentation Technology

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

1-702-714-7001Extn: 9037

Business & Management Journals


1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version