alexa [Epidemiologic and clinical aspects of Helicobacter pylori infection in children].


Journal of Nephrology & Therapeutics

Author(s): Torres J

Abstract Share this page

Abstract Worldwide, H. pylori prevalence in children ranges from under 10\% to almost 80\%. Prevalence is low in developed countries; whereas high prevalence is observed in most developing countries. Documented risk factors for infection include socioeconomic status, household crowding, ethnicity, migration from high prevalence regions, and infection status of family members. H. pylori infection is not associated with specific symptoms in children; although it is consistently associated with antral gastritis, which clinical significance is unclear. H. pylori associated duodenal ulcers are seldom seen in children under 10 years of age. The role of the infection in recurrent abdominal pain is highly controversial. H. pylori-infected children demonstrate a chronic inflammatory cell infiltrate, with a lack neutrophils, as compared with the response observed in adults. The importance of virulence determinants such as cagA and vacA, described as relevant for disease during H. pylori infection, has not been extensively studied in children. Sensitive and specific methods for the detection of H. pylori in children are needed, especially in infant populations where the colonization is in its early phases. Non-invasive, cheap, and simple methods are needed for epidemiologic studies. There is no consensus about criteria for the use of eradication treatment in H. pylori-infected children. Multicenter pediatric studies are needed to solve the many unanswered question on the natural history of H. pylori infection in children, including identification of risk factors for infection, identification of prognostic indicators for the development of gastroduodenal disease later in life, and the host response to infection.
This article was published in Rev Gastroenterol Mex and referenced in Journal of Nephrology & Therapeutics

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

1-702-714-7001Extn: 9037

Business & Management Journals


1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

1-702-714-7001Extn: 9042

General Science

Andrea Jason

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

1-702-714-7001Extn: 9042

© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version