Author(s): Williams RB, Henrikson JC, Hoover AR, Lee AE, Cichewicz RH
Abstract Share this page
Abstract Fungi treated with DNA methyltransferase and histone deacetylase inhibitors exhibited natural product profiles with enhanced chemical diversity demonstrating that small-molecule epigenetic modifiers are effective tools for rationally controlling the native expression of fungal biosynthetic pathways and generating new biomolecules.
This article was published in Org Biomol Chem
and referenced in Journal of Microbial & Biochemical Technology