alexa Estimation of aqueous solubility for some guanine derivatives using partition coefficient and melting temperature.
Pharmaceutical Sciences

Pharmaceutical Sciences

Journal of Bioequivalence & Bioavailability

Author(s): Kristl A

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Abstract Aqueous solubilities for some guanine derivatives were estimated by semiempirical equations developed by Yalkowsky and Valvani1 using the data for partition coefficient and melting temperature. It was shown that in the case of guanine derivatives examined in this study, the solubility values could not be estimated adequately by these equations. This article was published in J Pharm Sci and referenced in Journal of Bioequivalence & Bioavailability

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