alexa Evaluation of antipyretic potential of Cleome viscosa Linn. (Capparidaceae) extract in rats.


Journal of Pain Management & Medicine

Author(s): Devi BP, Boominathan R, Mandal SC, Devi BP, Boominathan R, Mandal SC, Devi BP, Boominathan R, Mandal SC, Devi BP, Boominathan R, Mandal SC

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Abstract The antipyretic activity of a methanol extract of Cleome viscosa Linn. (CVME) was investigated for its potential on normal body temperature and yeast-induced pyrexia in albino rats. The CVME, at doses of 200, 300, and 400mg/kg BW p.o., showed significant reduction in normal body temperature and yeast-provoked elevated temperature in a dose-dependent manner. The effect also extended upto 5h after the drug administration. The anti-pyretic effect of CVME was comparable to that of paracetamol (150mg/kg p.o.), a standard anti-pyretic agent.
This article was published in J Ethnopharmacol and referenced in Journal of Pain Management & Medicine

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