Author(s): Martini L, Lorenzini RN, Cinotti S, Fini M, Giavaresi G,
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Abstract This paper represents a contribution to researchers employing "in vivo" models in experimental surgery in order to obtain more reliable results in accordance with current legislation and Russel's "three R" statement: refinement, reduction, and replacement. After general consideration about the definition of pain and stress concerning laboratory animals, the authors suggest making an evaluation of the experimental protocol before approval by the local committee to allow assessment in terms of the costs/benefits of experimental research employing live animals. Copyright 2000 Academic Press.
This article was published in J Surg Res
and referenced in Journal of Anesthesia & Clinical Research