alexa Evaluation of the bactericidal efficacy of three different alcohol hand rubs against clinical isolates of Staphylococcus aureus using an ex vivo carrier test
Microbiology

Microbiology

Clinical Microbiology: Open Access

Author(s): KE Cheeseman, SP Denyer, IK Hosein, GJ Williams, JY Maillard

Abstract Share this page

We tested the efficacy of three alcohol hand rubs (AHRs) against Staphylococcus aureus using an ex vivo carrier test method and investigated the residual activity of AHRs and the effect of mechanical rubbing. A much longer contact time was required for the AHRs to achieve a bactericidal effect using the ex vivo test (between 10 and >20 min) compared with the in vitro test. Mechanical rubbing was found to increase the efficacy of the AHR compared to a rubbing control. Since the AHRs had no residual activity, the bactericidal effect achieved using the ex vivo test with contact times greater than the evaporation times (15 s) is unlikely to be achieved in practice. In view of such findings it is unlikely that AHRs are able to achieve a significant bactericidal effect (≥4 log(10) reduction) in practice, suggesting that contamination on the hands of healthcare workers (HCWs) may not be reduced enough to overcome the risk of cross-contamination and healthcare-associated infection. Since the AHRs had no residual effect they would be unable to prevent recolonisation of the hands of HCWs.

This article was published in J Hosp Infect and referenced in Clinical Microbiology: Open Access

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

agrifoodaquavet@omicsonline.com

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

clinical_biochem@omicsonline.com

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

business@omicsonline.com

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

chemicaleng_chemistry@omicsonline.com

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

environmentalsci@omicsonline.com

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

engineering@omicsonline.com

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

generalsci_healthcare@omicsonline.com

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

genetics_molbio@omicsonline.com

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

immuno_microbio@omicsonline.com

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

omics@omicsonline.com

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

materialsci@omicsonline.com

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

mathematics_physics@omicsonline.com

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

medical@omicsonline.com

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

neuro_psychology@omicsonline.com

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

pharma@omicsonline.com

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

social_politicalsci@omicsonline.com

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version