Author(s): van Diemen HA, Lanting P, Koetsier JC, Strijers RL, van Walbeek HK,
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Abstract In 22 patients with clinically definite multiple sclerosis (MS) who were without visual symptoms and had a visual acuity of at least 1.0 in both eyes at the time of measurement, the following tests were performed to detect subclinical lesions in the visual system: visual evoked potential (VEP), contrast sensitivity test (CS), flight of colours test (FOC), colour vision test (Ishihara plates) (CV) and the pupillary light reflex (PLR). VEP was abnormal in 81.8\%, CS in 72.7\%, FOC in 36.4\%, CV in 31.8\%, and PLR in 52.3\% of the patients. VEP and CS together were most sensitive: combining these techniques subclinical lesions of the visual system were detected in 90.9\% (20/22) of these asymptomatic patients.
This article was published in Clin Neurol Neurosurg
and referenced in Journal of Multiple Sclerosis