alexa Evaluation of two novel rapid rKE16 antigen-based tests for diagnosis of visceral leishmaniasis in India.
Genetics & Molecular Biology

Genetics & Molecular Biology

Journal of Molecular Biomarkers & Diagnosis

Author(s): Vaish M, Sharma S, Chakravarty J, Sundar S

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Abstract We compared the two formats of rKE16 antigen-based rapid tests, a flowthrough test (KEFT) and a lateral flow test (KELF), with the rK39 rapid test for the diagnosis of visceral leishmaniasis. Sensitivities with KEFT (99\%, 198/200) and rK39 (99.5\%, 199/200) were comparable and higher than that with KELF (95.5\%, 191/200). In the control groups comprising subjects with diseases from areas of nonendemicity or endemicity and subjects with different diseases, the specificities were comparable for all three rapid tests, except that specificity was higher with KELF in the controls from areas of endemicity.
This article was published in J Clin Microbiol and referenced in Journal of Molecular Biomarkers & Diagnosis

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