Author(s): Leszczynski DE, Kummerow FA
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Abstract Lysine and arginine supplements were fed to 5-day-old chicks to test whether they would develop hypercholesterolemia in response to excess lysine in a fashion similar to mammals. Chicks developed hypercholesterolemia with a 4-5\% lysine but not with arginine supplementation. These results indicate the lysine induced hypercholesterolemia is not due to anaplerotic interactions of arginine and lysine with the urea cycle.
This article was published in Experientia
and referenced in Journal of Molecular and Genetic Medicine