Author(s): Nishi S, Hoshi N, Kasahara M, Ishibashi T, Fujimoto S
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Abstract The human deleted in azoospermia-like autosomal (DAZLA) gene is thought to be a candidate gene for azoospermia. cDNA encoding the C-terminal 94 amino acid residues of human DAZLA was used to express a bacterial fusion protein which was then used to raise polyclonal antibodies in rabbits. Immunohistochemical analyses with the human DAZLA antiserum showed that the DAZLA protein is expressed at a cytoplasmic location in female germ cells. Available evidence suggests that the DAZLA gene is a participant in human oogenesis.
This article was published in Mol Hum Reprod
and referenced in Reproductive System & Sexual Disorders: Current Research