alexa Experience with aspiration in cases of amebic liver abscess in an endemic area.


Journal of Gastrointestinal & Digestive System

Author(s): Khanna S, Chaudhary D, Kumar A, Vij JC

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Abstract The study presented here was performed to evaluate the need for aspiration in patients with amebic liver abscess (ALA). Patients older than 12 years with a diagnosis of ALA based on clinical features, ultrasound results, and positive amebic serology were included in the study (n=144). Serological testing was performed to detect the presence of immunoglobin G antibody against Entamoeba histolytica, and a value of more than 0.4 optical density units was considered positive. All patients were given intravenous metronidazole (500 mg every 8 h) and their clinical progress and need for abscess aspiration was documented. Fever, pain in the upper abdomen, and tender hepatomegaly was seen in 133 (92.3\%), 128 (88.8\%), and 144 (100\%) patients, respectively. Multiple abscesses were seen in 40 (27.7\%) patients. Six (4.1\%) patients died. Seventy-one (49.3\%) patients responded to metronidazole alone. A total of 73 (50.69\%) patients required aspiration of the abscess. This study shows that almost 50\% of the patients with amebic liver abscess failed to respond to metronidazole and required aspiration. This article was published in Eur J Clin Microbiol Infect Dis and referenced in Journal of Gastrointestinal & Digestive System

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