Author(s): Aubin F, Cahn JY, Ferrand C, Angonin R, Humbert P, , Aubin F, Cahn JY, Ferrand C, Angonin R, Humbert P,
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Abstract The use of donor T cells expressing a suicide gene for destruction of graft-versus-host effector cells provides a tool for alloreactivity modulation. We describe a case of extensive vitiligo that developed after ganciclovir treatment of cutaneous chronic graft-versus-host disease in a patient who had received donor T lymphocytes expressing herpes simplex virus thymidine kinase at the time of transplantation.
This article was published in Lancet
and referenced in Dermatology and Dermatologic Diseases