Author(s): Knudsen TE, NielsenKudsk JE
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Abstract A case of fatal fulminant hepatitis following treatment with disulphiram in a man aged 34 year is reported. Acute toxic hepatitis produced by disulphiram is a rare but serious side effect with a lethality about 40\%. In the case reported here, immediate withdrawal of disulphiram administration on the earliest signs of hepatitis did not prevent toxic development of severe hepatic necrosis.
This article was published in Ugeskr Laeger
and referenced in Journal of Microbial & Biochemical Technology