Author(s): Thulstrup AM, Srensen HT, Nielsen GL, Andersen L, Barrett D,
Abstract Share this page
Abstract We studied the association between acetaminophen exposure during pregnancy and the prevalence of congenital abnormalities and fetal growth. Our study included 123 women who had received a prescription of acetaminophen during pregnancy and/or 30 days before conception and 13,329 controls who did not receive any prescription at all. We found more malformations among those who received a prescription with an odds ratio of 2.3 (95\% CI 1.0-5.4), but the type of malformations did not indicate a causal link. When restricting the study to first time pregnancies, we identified 58 women who received a prescription of acetaminophen during pregnancy and 30 days before conception and 7472 controls. We found no excess risk of malformation [OR = 0.7 (95\% CI 0.1-5.5)], and no evidence that acetaminophen should influence fetal growth.
This article was published in Am J Perinatol
and referenced in Dentistry