alexa Flavonol glycosides from the leaves of Eucommia ulmoides O. with glycation inhibitory activity.
Diabetes & Endocrinology

Diabetes & Endocrinology

Journal of Diabetes & Metabolism

Author(s): Kim HY, Moon BH, Lee HJ, Choi DH

Abstract Share this page

Abstract Eucommia ulmoides leaves have been used as a folk remedy for the treatment of diabetes in Korea. The aim of this study was to isolate and identify the compounds which inhibited advanced glycation end-product formation, one of main molecular mechanisms implicated in diabetic complications. A new flavonol glycoside, quercetin 3-O-alpha-L-arabinopyranosyl-(1-->2)-beta-D-glucopyranoside (1), and known flavonols kaempferol 3-O-beta-D-glucopyranoside (astragalin) (2), quercetin 3-O-beta-D-glucopyranoside (isoquercitrin) (3) were isolated from the leaves of Eucommia ulmoides. These compounds exhibited glycation inhibitory activity comparable to that of aminoguanidine, a known glycation inhibitor. The results suggest that the flavonol glycosides with glycation inhibitory activity could be attributed to the anti-diabetic action of Eucommia ulmoides leaves. This article was published in J Ethnopharmacol and referenced in Journal of Diabetes & Metabolism

Relevant Expert PPTs

Relevant Speaker PPTs

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords